jeudi 28 juin 2012

Théorie des humeurs, version biochimique

Au lycée j'aimais bien le cours de sciences nat, y'a tellement de trucs qu'on a oublié de m'apprendre parce qu'on le savait pas à l'époque. Aujourd'hui trois concepts à méditer: axe HPA, axe HPG et charge allostatique:

  • Allostatic load. Allostasis, meaning literally "maintaining stability (or homeostasis) through change" was introduced by Sterling and Eyer to describe how the cardiovascular system adjusts to resting and active states of the body. This notion can be applied to other physiological mediators, such as the secretion of cortisol as well as catecholamines, and the concept of "allostatic load" was proposed to refer to the wear and tear that the body experiences due to repeated cycles of allostasis as well as the inefficient turning-on or shutting off of these responses.
  • HPA axis: Mon régulateur d'énergie. The hypothalamic-pituitary-adrenal axis is a complex set of interactions between the hypothalamus (a part of the brain), the pituitary gland (also part of the brain) and the adrenal or suprarenal glands (at the top of each kidney.) The HPA axis helps regulate things such as your temperature, digestion, immune system, mood, sexuality and energy usage. It's also a major part of the system that controls your reaction to stress, trauma and injury.
  • HPG axis: The hypothalamic–pituitary–gonadal axis is a critical part in the development and regulation of a number of the body's systems, such as the reproductive and immune systems. Fluctuations in the hormones cause changes in the hormones produced by each gland and have various widespread and local effects on the body. This axis controls development, reproduction, and aging in animals.

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